In the complex world of neurology, where the mysteries of the central nervous system are unraveled, ARCS scholar Nathan Anderson's MS research at the University of Oregon stands out as a unique blend of scientific inquiry and personal mission. Nathan's work focuses on a protein called Vnd, a key player in developing neurons and glial cells in insects. These cells are vital for basic life functions.
Nathan's research aims to discover how stem cells in the central nervous system differentiate into the various cells necessary for an organism's survival. However, what makes Nathan's work particularly relevant to multiple sclerosis (MS) is the vertebrate counterpart of Vnd—NKX2.2. This key protein increases around MS lesions and is crucial for the cells that myelinate neurons in the central nervous system.
By what Nathan describes as pure serendipity, his research into Vnd has become directly relevant to the pathology of MS. This connection between his scientific work and the disease he has been battling since he was 17 years old provides Nathan with a unique perspective and motivation in his PhD journey.
A Friendship Forged in Shared Struggles
Nathan's connection with MS goes beyond his own diagnosis and research. Three years ago, he met ARCS Oregon member Lara Ogg at the ARCS Scholar Picnic. Lara's mother, Caron Ogg, also an ARCS member, introduced them after discovering Nathan's background in neurology and his diagnosis of MS, a disease that also affects Lara.
Lara and Nathan became friends that day at the picnic, finding in each other a source of support and understanding. They've exchanged tips on managing the disease, from diet and exercise to the latest research developments.
The Invisible Burden of Chronic Illness
Living with a chronic illness like MS involves much more than the visible symptoms. For Nathan, the most challenging aspects are the constant fatigue and the resulting struggles that accompany the disease. These invisible burdens can make daily life and common routines a daunting task.
Nathan acknowledges that it's difficult for those without chronic illness to fully understand these challenges, but he believes it's important to talk about them. By raising awareness, he hopes to foster a sense of empathy—not just for MS patients, but for anyone living with a chronic illness.
The Importance of Community
For Nathan, the support and friendship of people who understand MS has been crucial to his success in the PhD program. The encouragement he receives from friends like Lara, his mother in Idaho (who also has MS), and Caron, his "Oregon Mom," has helped him stay focused on his research, even on tough days when making an impact in the field seems distant.
Nathan's journey is a testament to the power of community in the face of neurodegenerative illness. The moments of doubt he experiences are becoming increasingly rare as he progresses in his studies, thanks in no small part to the unwavering support of his friends and loved ones.
As Lara reflects on their conversations about MS, one of Nathan's quotes stands out: "MS is RUDE." This statement resonates deeply with her, capturing the frustration and unrelenting nature of the disease. Yet, Nathan's determination is equally inspiring. "MS, I'm coming for you," he says, embodying the fighting spirit of a scholar who is not only studying the disease but living with it.
Nathan's discovery that the protein he studied in fruit flies is the same one involved in MS lesions has given him renewed focus in his research. For Lara, knowing a scientist on the front lines of MS research is a source of hope and inspiration. Nathan's work, driven by both personal and professional motivations, holds the potential to make a meaningful impact on the lives of those affected by MS.
In a world where the intersection of science and personal experience can lead to groundbreaking discoveries, Nathan's journey offers a powerful reminder of the resilience and determination that drive the search for a cure.
